Cyclic AMP‐hydrolyzing phosphodiesterase inhibitors potentiate statin‐induced cancer cell death-Reference-Cited by-同舟云学术

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Cyclic AMP‐hydrolyzing phosphodiesterase inhibitors potentiate statin‐induced cancer cell death

Published:2020-08-25 Issue:10 Volume:14 Page:2533-2545
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:Mol Oncol

Author:

Longo Joseph¹²^ORCID,Pandyra Aleksandra A.¹²³⁴,Stachura Paweł³,Minden Mark D.¹²,Schimmer Aaron D.¹²,Penn Linda Z.¹²^ORCID

Affiliation:

1. Princess Margaret Cancer Centre University Health Network Toronto Canada

2. Department of Medical Biophysics University of Toronto Toronto Canada

3. Department of Molecular Medicine II Medical Faculty Heinrich Heine University Düsseldorf Germany

4. Department of Gastroenterology, Hepatology, and Infectious Diseases Heinrich Heine University Düsseldorf Germany

Funder

Canadian Cancer Society Research Institute

Canada Research Chairs

Canadian Institutes of Health Research

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.12775

Reference53 articles.

1. The interplay between cell signalling and the mevalonate pathway in cancer

2. Exploiting the mevalonate pathway to distinguish statin-sensitive multiple myeloma

3. Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells

4. An actionable sterol-regulated feedback loop modulates statin sensitivity in prostate cancer

5. Genome-wide RNAi analysis reveals that simultaneous inhibition of specific mevalonate pathway genes potentiates tumor cell death

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