An unbiased high‐throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer

Author:

Pan Chun‐Hao12ORCID,Otsuka Yuka3,Sridharan BanuPriya4,Woo Melissa15,Leiton Cindy V.1,Babu Sruthi16,Torrente Gonçalves Mariana1,Kawalerski Ryan R.1,K. Bai Ji Dong1,Chang David K.78,Biankin Andrew V.78,Scampavia Louis3,Spicer Timothy3,Escobar‐Hoyos Luisa F.191011,Shroyer Kenneth R.1ORCID

Affiliation:

1. Department of Pathology Renaissance School of Medicine Stony Brook University NY USA

2. Molecular and Cellular Biology Graduate Program Stony Brook University NY USA

3. The Scripps Research Institute Jupiter FL USA

4. In vitro In vivo Translation GSK, Collegeville PA USA

5. Simons Summer Research Program Stony Brook University NY USA

6. Department of Family, Population & Preventive Medicine Renaissance School of Medicine Stony Brook University NY USA

7. Wolfson Wohl Cancer Research Centre Institute of Cancer Sciences University of Glasgow UK

8. West of Scotland Pancreatic Unit Glasgow Royal Infirmary UK

9. Department of Therapeutic Radiology School of Medicine Yale University New Haven CT USA

10. David M. Rubenstein Center for Pancreatic Cancer Research Memorial Sloan Kettering Cancer Center New York NY USA

11. Genetic Toxicology and Cytogenetics Research Group Department of Biology School of Natural Sciences and Education Universidad del Cauca Popayán Colombia

Funder

National Pancreas Foundation

National Cancer Institute

Pancreatic Cancer Action Network

National Institutes of Health

Hirshberg Foundation for Pancreatic Cancer Research

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

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