Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

Author:

Severson Tesa M.12,Zhu Yanyun1,De Marzo Angelo M.3,Jones Tracy4,Simons Jonathan W.5,Nelson William G.3,Yegnasubramanian Srinivasan6,Freedman Matthew L.78,Wessels Lodewyk2,Bergman Andries M.19,Haffner Michael C.10114,Zwart Wilbert112ORCID

Affiliation:

1. Division of Oncogenomics Oncode Institute Netherlands Cancer Institute Amsterdam the Netherlands

2. Division of Molecular Oncogenesis Oncode Institute Netherlands Cancer Institute Amsterdam the Netherlands

3. Sidney Kimmel Comprehensive Cancer Center Department of Pathology Brady Urological Institute Johns Hopkins School of Medicine Baltimore MD USA

4. Department of Pathology Johns Hopkins School of Medicine Baltimore MD USA

5. Prostate Cancer Foundation Santa Monica CA USA

6. Sidney Kimmel Comprehensive Cancer Center Johns Hopkins School of Medicine Baltimore MD USA

7. Department of Medical Oncology Dana‐Farber Cancer Institute Harvard Medical School Boston MA USA

8. The Eli and Edythe L. Broad Institute Cambridge MA USA

9. Department of Medical Oncology Netherlands Cancer Institute Amsterdam the Netherlands

10. Divisions of Human Biology and Clinical Research Fred Hutchinson Cancer Research Center Seattle WA USA

11. Department of Pathology University of Washington Seattle WA USA

12. Laboratory of Chemical Biology and Institute for Complex Molecular Systems Department of Biomedical Engineering Eindhoven University of Technology Eindhoven the Netherlands

Funder

KWF Kankerbestrijding

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

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