Intrinsic and acquired drug resistance to LSD1 inhibitors in small cell lung cancer occurs through a TEAD4‐driven transcriptional state-Reference-Cited by-同舟云学术

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Intrinsic and acquired drug resistance to LSD1 inhibitors in small cell lung cancer occurs through a TEAD4‐driven transcriptional state

Published:2021-11-09 Issue: Volume: Page:
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:Molecular Oncology

Author:

Yan Wen¹^ORCID,Chung Chi‐Yeh¹,Xie Tao¹,Ozeck Mark¹,Nichols Timothy C.¹,Frey Jessica¹,Udyavar Akshata R.²,Sharma Shikhar¹,Paul Thomas A.¹^ORCID

Affiliation:

1. Oncology Research Discovery Pfizer Worldwide Research and Development San Diego CA USA

2. Arcus Biosciences Hayward CA USA

Funder

Pfizer

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.13124

Reference58 articles.

1. Comprehensive genomic profiles of small cell lung cancer

2. Phase II Study of the Histone Deacetylase Inhibitor Romidepsin in Relapsed Small Cell Lung Cancer (Cancer and Leukemia Group B 30304)

3. Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression

4. DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2

5. A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC

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1. Upregulation of CDC25B by transcription factor TEAD4 drives invasion and inhibits cisplatin sensitivity through cell adhesion in stomach adenocarcinoma;Anti-Cancer Drugs;2024-07-23

2. Genes diferencialmente expresados en cáncer de pulmón de células pequeñas: Potenciales dianas terapéuticas;Ars Pharmaceutica (Internet);2024-06-20

3. TEAD4: A key regulator of tumor metastasis and chemoresistance - Mechanisms and therapeutic implications;Biochimica et Biophysica Acta (BBA) - Reviews on Cancer;2024-01

4. Actionable Driver Events in Small Cell Lung Cancer;International Journal of Molecular Sciences;2023-12-20

5. A review of recent advances in the novel therapeutic targets and immunotherapy for lung cancer;Medical Oncology;2023-04-18

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