Epigenetic–smoking interaction reveals histologically heterogeneous effects of TRIM27 DNA methylation on overall survival among early‐stage NSCLC patients

Author:

Ji Xinyu1,Lin Lijuan12,Shen Sipeng123,Dong Xuesi124,Chen Chao1,Li Yi5,Zhu Ying1,Huang Hui1,Chen Jiajin1,Chen Xin1,Wei Liangmin1,He Jieyu1,Duan Weiwei16,Su Li2,Jiang Yue1,Fan Juanjuan1,Guan Jinxing1,You Dongfang12,Shafer Andrea7,Bjaanæs Maria Moksnes8,Karlsson Anna9,Planck Maria9,Staaf Johan9,Helland Åslaug810,Esteller Manel11121314ORCID,Wei Yongyue123ORCID,Zhang Ruyang123ORCID,Chen Feng131516ORCID,Christiani David C.27

Affiliation:

1. Department of Biostatistics Center for Global Health School of Public Health Nanjing Medical University Nanjing China

2. Department of Environmental Health Harvard T.H. Chan School of Public Health Boston MA USA

3. China International Cooperation Center for Environment and Human Health Nanjing Medical University Nanjing China

4. Department of Epidemiology and Biostatistics School of Public Health Southeast University Nanjing China

5. Department of Biostatistics University of Michigan Ann Arbor MI USA

6. Department of Bioinformatics School of Biomedical Engineering and Informatics Nanjing Medical University Nanjing China

7. Pulmonary and Critical Care Division Department of Medicine Massachusetts General Hospital and Harvard Medical School Boston MA USA

8. Department of Cancer Genetics Institute for Cancer Research Oslo University Hospital Oslo Norway

9. Division of Oncology and Pathology Department of Clinical Sciences Lund and CREATE Health Strategic Center for Translational Cancer Research Lund University Lund Sweden

10. Institute of Clinical Medicine University of Oslo Oslo Norway

11. Josep Carreras Leukaemia Research Institute Badalona, Barcelona Spain

12. Centro de Investigacion Biomedica en Red Cancer Madrid Spain

13. Institucio Catalana de Recerca i Estudis Avançats Barcelona Spain

14. Physiological Sciences Department School of Medicine and Health Sciences University of Barcelona Barcelona Spain

15. State Key Laboratory of Reproductive Medicine Nanjing Medical University Nanjing China

16. Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment Cancer Center Collaborative Innovation Center for Cancer Personalized Medicine Nanjing Medical University Nanjing China

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

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