USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K-Reference-Cited by-同舟云学术

USP28 enables oncogenic transformation of respiratory cells, and its inhibition potentiates molecular therapy targeting mutant EGFR, BRAF and PI3K

Published:2022-04-30 Issue:17 Volume:16 Page:3082-3106
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:Molecular Oncology

Author:

Prieto‐Garcia Cristian¹²³,Hartmann Oliver¹²,Reissland Michaela¹²^ORCID,Braun Fabian¹²,Bozkurt Süleyman⁴^ORCID,Pahor Nikolett¹²,Fuss Carmina¹²⁵,Schirbel Andreas⁶,Schülein‐Völk Christina⁷,Buchberger Alexander⁸^ORCID,Calzado Canale Marco A.⁹¹⁰¹¹,Rosenfeldt Mathias²¹²,Dikic Ivan³¹³^ORCID,Münch Christian⁴,Diefenbacher Markus E.¹²^ORCID

Affiliation:

1. Protein Stability and Cancer Group Department of Biochemistry and Molecular Biology University of Wuerzburg Germany

2. Mildred Scheel Early Career Center Wuerzburg Germany

3. Molecular Signaling Group Institute of Biochemistry II Goethe University Frankfurt Germany

4. Protein Quality Control Institute of Biochemistry II Goethe University Frankfurt Germany

5. Division of Endocrinology and Diabetes Department of Internal Medicine I University Hospital University of Wuerzburg Germany

6. Department of Nuclear Medicine University Hospital University of Wuerzburg Germany

7. Core Unit High‐Content Microscopy Biocenter University of Wuerzburg Germany

8. Department of Biochemistry Biocenter University of Wuerzburg Germany

9. Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC) Spain

10. Departamento de Biología Celular, Fisiología e Inmunología Universidad de Córdoba Spain

11. Hospital Universitario Reina Sofía Córdoba Spain

12. Institut für Pathologie Universitaetsklinikum Wuerzburg Germany

13. Buchmann Institute for Molecular Life Sciences Goethe University Frankfurt Germany

Funder

Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg

Deutsche Forschungsgemeinschaft

German-Israeli Foundation for Scientific Research and Development

Deutsche Krebshilfe

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/1878-0261.13217

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