Intracranial AAV-IFN-β gene therapy eliminates invasive xenograft glioblastoma and improves survival in orthotopic syngeneic murine model-Reference-Cited by-同舟云学术

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Intracranial AAV-IFN-β gene therapy eliminates invasive xenograft glioblastoma and improves survival in orthotopic syngeneic murine model

Published:2017-01-18 Issue:2 Volume:11 Page:180-193
ISSN:1574-7891
Container-title:Molecular Oncology
language:en
Short-container-title:Mol Oncol

Author:

GuhaSarkar Dwijit¹²^ORCID,Neiswender James¹²,Su Qin¹,Gao Guangping¹³,Sena-Esteves Miguel¹²

Affiliation:

1. Horae Gene Therapy Center; University of Massachusetts Medical School; Worcester MA USA

2. Department of Neurology; University of Massachusetts Medical School; Worcester MA USA

3. Department of Microbiology and Physiological Systems; University of Massachusetts Medical School; Worcester MA USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Cancer Research,Genetics,Molecular Medicine,General Medicine,Oncology

Reference36 articles.

1. Pharmacokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers;Buchwalder;J Interferon Cytokine Res,2000

2. Tetracycline-inducible transgene expression mediated by a single AAV vector;Chtarto;Gene Ther,2003

3. Continuous local delivery of interferon-beta stabilizes tumor vasculature in an orthotopic glioblastoma xenograft resection model;Denbo;Surgery,2011

4. Systemic AAV9-IFN-β gene delivery treats highly invasive glioblastoma;GuhaSarkar;Neuro Oncol,2016

5. The role of microglia and macrophages in glioma maintenance and progression;Hambardzumyan;Nat Neurosci,2016

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