Genetic variants of organic cation transporter 1 (OCT1) and OCT2 significantly reduce lamivudine uptake
Author:
Affiliation:
1. College of Pharmacy; Dankook University; Cheon-an; 330-714; Korea
Publisher
Wiley
Subject
Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/bdd.1783/fullpdf
Reference24 articles.
1. Clinical pharmacokinetics of lamivudine;Johnson;Clin Pharmacokinet,1999
2. The effect of ABCG2 V12M, Q141K and Q126X, known functional variants in vitro, on the disposition of lamivudine;Kim;Br J Clin Pharmacol,2007
3. Uptake of lamivudine by rat renal brush border membrane vesicles;Takubo;J Pharm Pharmacol,2002
4. Uptake properties of lamivudine (3TC) by a continuous renal epithelial cell line;Leung;Can J Physiol Pharmacol,2001
5. Relevance of the organic cation transporters 1 and 2 for antiretroviral drug therapy in human immunodeficiency virus infection;Jung;Drug Metab Dispos,2008
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