Hepatic CREBZF couples insulin to lipogenesis by inhibiting insig activity and contributes to hepatic steatosis in diet‐induced insulin‐resistant mice

Author:

Zhang Feifei1,Hu Zhimin1,Li Gaopeng2,Huo Shaofeng1,Ma Fengguang1,Cui Aoyuan1,Xue Yaqian1,Han Yamei1,Gong Qi1,Gao Jing1,Bian Hua34,Meng Zhuoxian5,Wu Haifu6,Long Gang7,Tan Yi8,Zhang Yan2,Lin Xu1,Gao Xin34,Xu Aimin91011,Li Yu1ORCID

Affiliation:

1. CAS Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological SciencesUniversity of Chinese Academy of Sciences, Chinese Academy of Sciences Shanghai China

2. College of Life Sciences and OceanographyShenzhen University Shenzhen Guangdong China

3. Department of Endocrinology and Metabolism, Zhongshan HospitalFudan University Shanghai China

4. Fudan Institute for Metabolic Diseases Shanghai China

5. Department of Pathology and PathophysiologyZhejiang University School of Medicine Hangzhou Zhejiang China

6. Metabolic and Bariatric Surgery of Department of General Surgery, Zhongshan HospitalFudan University Shanghai China

7. Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of ShanghaiChinese Academy of Sciences Shanghai China

8. Pediatric Research Institute at the Department of Pediatrics, Wendy L. Novak Diabetes Care CenterUniversity of Louisville Louisville KY

9. State Key Laboratory of Pharmaceutical BiotechnologyThe University of Hong Kong Hong Kong China

10. Department of MedicineThe University of Hong Kong Hong Kong China

11. Department of Pharmacology and PharmacyThe University of Hong Kong Hong Kong China

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

Wiley

Subject

Hepatology

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