A phase 1 study of ACE‐536, a regulator of erythroid differentiation, in healthy volunteers
Author:
Affiliation:
1. Acceleron Pharma IncCambridge Massachusetts
2. CelerionTempe Arizona
Publisher
Wiley
Subject
Hematology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajh.23732
Reference15 articles.
1. Clinical Pharmacokinetics and Pharmacodynamics of Erythropoiesis-Stimulating Agents
2. Complex and Context Dependent Regulation of Hematopoiesis by TGF-β Superfamily Signaling
3. Stromal cell-mediated inhibition of erythropoiesis can be attenuated by Sotatercept (ACE-011), an activin receptor type II ligand trap
4. β-thalassemia: a model for elucidating the dynamic regulation of ineffective erythropoiesis and iron metabolism
5. Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin
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