Multisystem inflammatory syndrome in adult with features of Kawasaki disease

Author:

Heng Li Wei1ORCID,Ong Geraldine H. M.2ORCID,Lee Oswald Z. J.3,Liau MeiQi May2ORCID

Affiliation:

1. Department of Medicine National University Health System Singapore

2. Department of Medicine, Division of Dermatology National University Health System Singapore

3. Department of Pathology National University Health System Singapore

Abstract

AbstractWe present a case of a 21‐year‐old woman with fever (>38.0°C) for 5 days, mucocutaneous lesions and refractory hypotension requiring dual inotropic support. The only significant past medical history was an episode of COVID infection 4 months before admission. She was diagnosed to have multisystem inflammatory syndrome in adult (MIS‐A)—a relatively new entity which occurs as a severe complication in patients post‐COVID‐19 infection. This condition can present remarkably similarly to Kawasaki disease. Although the paediatric counterpart of MIS‐A typically occurs within 2–6 weeks post COVID‐19 infection, MIS‐A may occur up to 4 months post‐COVID‐19 infection. We wish to raise awareness of this rare entity, their similarities with Kawasaki disease and the importance of early initiation of intravenous immunoglobulin and high‐dose aspirin.

Publisher

Wiley

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