Engineering oncolytic vaccinia virus to redirect macrophages to tumor cells

Author:

Cao Felicia123,Nguyen Phuong1456,Hong Bangxing1,DeRenzo Christopher145,Rainusso Nino C.45,Rodriguez Cruz Tania1,Wu Meng‐Fen7,Liu Hao8,Song Xiao‐Tong1,Suzuki Masataka1,Wang Lisa L.45,Yustein Jason T.45,Gottschalk Stephen1456ORCID

Affiliation:

1. Center for Cell and Gene Therapy Texas Children’s HospitalHouston Methodist HospitalBaylor College of Medicine Houston TX USA

2. Interdepartmental Program in Translational Biology and Molecular Medicine Baylor College of Medicine Houston TX USA

3. Medical Scientist Training Program Baylor College of Medicine Houston TX USA

4. Texas Children’s Cancer and Hematology CentersTexas Children’s HospitalBaylor College of Medicine Houston TX USA

5. Department of Pediatrics Baylor College of Medicine Houston TX USA

6. Department of Bone Marrow Transplantation and Cellular Therapy St. Jude Children’s Research Hospital Memphis TN USA

7. Biostatistics Shared Resource Dan L Duncan Cancer Center Baylor College of Medicine Houston TX USA

8. Department of Biostatistics Indiana University School of Medicine Indianapolis IN USA

Publisher

Hindawi Limited

Reference59 articles.

1. Oncolytic Virotherapy: A Contest between Apples and Oranges

2. Targeted and armed oncolytic poxviruses: a novel multi-mechanistic therapeutic class for cancer

3. Oncolytic virotherapy

4. Phase I Trial of Intravenous Oncolytic Vaccinia Virus (GL-ONC1) with Cisplatin and Radiotherapy in Patients with Locoregionally Advanced Head and Neck Carcinoma

5. Open‐label phase II study evaluating the efficacy and safety of Talimogene Laherparepvec in combination with ipilimumab versus ipilimumab alone in patients with advanced, unresectable melanoma;Chesney J;J Clin Oncol.,2017

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