Improved assembly of bispecific antibodies from knob and hole half-antibodies
Author:
Affiliation:
1. Dept. of Purification Development; Pharma Technical Development, Genentech; South San Francisco CA
Publisher
Wiley
Subject
Biotechnology
Reference19 articles.
1. Metrics for antibody therapeutics development;Reichert;mAbs,2010
2. Antitumor efficacy of a bispecific antibody that targets HER2 and activates T cells;Junttila;Cancer Res,2014
3. Therapeutic bispecific antibodies cross the blood-brain barrier in nonhuman primates;Yu;Sci Transl Med,2014
4. ‘Knobs-into-holes’ engineering of antibody CH3 domains for heavy chain heterodimerization;Ridgway;Protein Eng,1996
5. Development of a human IgG4 bispecific antibody for dual targeting of interleukin-4 (IL-4) and interleukin-13 (IL-13) cytokines;Spiess;J Biol Chem,2013
Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Structural study of a light chain mispaired bispecific predicts mechanism of downstream separation;Journal of Chromatography A;2024-08
2. Large scale controlled Fab exchange GMP process to prepare bispecific antibodies;Frontiers in Bioengineering and Biotechnology;2024-01-12
3. Bioprocess Development and Characterization of a 13C-Labeled Hybrid Bispecific Antibody Produced in Escherichia coli;Antibodies;2023-02-14
4. CLEC5a-directed bispecific antibody for effective cellular phagocytosis;mAbs;2022-03-16
5. Chapter 4: Production Strategies and Challenges with IgG-Based Bispecific Ab Formats;Development of Biopharmaceutical Drug-Device Products;2020
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3