Drug-induced allergic hepatitis develops in mice when myeloid-derived suppressor cells are depleted prior to halothane treatment

Author:

Chakraborty Mala1,Fullerton Aaron M.1,Semple Kenrick1,Chea Lynette S.1,Proctor William R.1,Bourdi Mohammed1,Kleiner David E.2,Zeng Xiangbin1,Ryan Pauline M.1,Dagur Pradeep K.3,Berkson Julia D.1,Reilly Timothy P.4,Pohl Lance R.1

Affiliation:

1. Molecular and Cellular Toxicology Section, Laboratory of Molecular Immunology; National Heart, Lung and Blood Institute, National Institutes of Health; Bethesda MD

2. Laboratory of Pathology; National Cancer Institute; National Institutes of Health; Bethesda MD

3. Hematology Branch, National Heart; Lung and Blood Institute; National Institutes of Health; Bethesda MD

4. Exploratory Clinical & Translational Research; Bristol-Myers Squibb Company; Princeton NJ

Funder

Office of Extramural Research, National Institutes of Health

Publisher

Wiley

Subject

Hepatology

Reference37 articles.

1. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States;Ostapowicz;Ann Intern Med,2002

2. Drug-induced allergic hepatitis;Pohl;Semin Liver Dis,1990

3. Immune-mediated drug-induced liver disease;Liu;Clin Liver Dis,2002

4. Evaluation of isoniazid-associated hepatitis by immunological tests;Warrington;Clin Exp Immunol,1978

5. Drug-specific T cells derived from patients with drug-induced allergic hepatitis;Tsutsui;J Immunol,1992

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