Sex‐dependent clinical presentation, body image, and endocrine status in long‐term remitted anorexia nervosa

Author:

Schloesser Louisa12ORCID,Lotter Leon D.1345ORCID,Offermann Jan1,Borucki Katrin6,Biemann Ronald7,Seitz Jochen2ORCID,Konrad Kerstin18ORCID,Herpertz‐Dahlmann Beate2ORCID

Affiliation:

1. Child Neuropsychology Section Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy University Hospital RWTH Aachen Aachen Germany

2. Department of Child and Adolescent Psychiatry Psychosomatics and Psychotherapy University Hospital RWTH Aachen Aachen Germany

3. Institute of Neuroscience and Medicine, Brain & Behaviour (INM‐7) Jülich Research Centre Jülich Germany

4. Institute of Systems Neuroscience Medical Faculty Heinrich Heine University Düsseldorf Düsseldorf Germany

5. Max Planck School of Cognition Leipzig Germany

6. Institute for Clinical Chemistry and Pathobiochemistry Otto von Guericke University Magdeburg Magdeburg Germany

7. Institute for Laboratory Medicine Clinical Chemistry and Molecular Diagnostics University Hospital Leipzig Leipzig Germany

8. JARA‐Brain Institute II Molecular Neuroscience and Neuroimaging Jülich Research Centre Jülich Germany

Abstract

AbstractObjectiveAlthough anorexia nervosa (AN) in males has recently gained attention, knowledge of its psychological and physiological outcomes is still scarce. We explore sex‐specific characteristics of long‐term remitted AN with respect to residual eating disorder (ED) psychopathology, body image, and endocrinology.MethodWe recruited 33 patients with AN in remission for at least 18 months (24 women, 9 men) and 36 matched healthy controls (HCs). Eating disorder psychopathology and body image ideals were assessed via clinical interviews, questionnaires, and an interactive 3D body morphing tool. Plasma levels of leptin, free triiodothyronine, cortisol, and sex hormones were quantified. Univariate models controlled for age and weight were used to test for the effects of diagnosis and sex.ResultsBoth patient groups showed residual ED psychopathology but normal weight and hormone levels relative to HCs. Male remitted patients demonstrated significantly stronger muscularity‐focused body image ideals, evident in interviews, self‐reports, and behavioural data, than both female patients and HCs.ConclusionsSex‐specific body image characteristics in patients with remitted AN point towards the need to adjust test instruments and diagnostic criteria to male‐specific psychopathology. In the future, sufficiently powered studies should evaluate the risk of men with AN developing muscle dysmorphia in the long term.

Funder

Schweizerische Anorexia Nervosa Stiftung

Bundesministerium für Bildung und Forschung

Max-Planck-Gesellschaft

Publisher

Wiley

Subject

Psychiatry and Mental health,Clinical Psychology

Reference64 articles.

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