Functional characterization of the defective CYP2C9 variant CYP2C9*18-Reference-Cited by-同舟云学术

Functional characterization of the defective CYP2C9 variant CYP2C9*18

Published:2021-01-28 Issue:1 Volume:9 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol. Res. Perspect.

Author:

Liu Jian¹,Chen Hao²,Wang Shuang‐Hu³,Zhou Quan³,Geng Pei‐Wu³,Zhou Yun‐Fang³,Wu Hua‐Lan²,Shi Hai‐Feng²,Wang Fang²,Yang Jie‐Fu²,Cai Jian‐Ping¹,Dai Da‐Peng¹^ORCID

Affiliation:

1. The Key laboratory of Geriatrics Beijing Institute of GeriatricsBeijing HospitalNational Center of GerontologyNational Health CommissionInstitute of Geriatric MedicineChinese Academy of Medical Sciences Beijing P. R. China

2. Cardiovascular Department Beijing HospitalNational Center of GerontologyInstitute of Geriatric MedicineChinese Academy of Medical Sciences Beijing P. R. China

3. Laboratory of Clinical Pharmacy The Sixth Affiliated Hospital of Wenzhou Medical UniversityThe People's Hospital of Lishui Lishui P.R. China

Funder

National Natural Science Foundation of China

Capital Health Research and Development of Special

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.718

Reference27 articles.

1. Pharmacogenetics of Warfarin Elimination and its Clinical Implications

2. Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

3. Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

4. CYP2C9 allelic variants: ethnic distribution and functional significance

5. Cytochrome P450: genotype to phenotype

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