Ayahuasca: A review of historical, pharmacological, and therapeutic aspects-Reference-Cited by-同舟云学术

Ayahuasca: A review of historical, pharmacological, and therapeutic aspects

Published:2023-10-02 Issue:4 Volume:2 Page:
ISSN:2769-2558
Container-title:Psychiatry and Clinical Neurosciences Reports
language:en
Short-container-title:PCN Reports

Author:

Ruffell Simon G. D.¹²³,Crosland‐Wood Max¹⁴,Palmer Rob¹⁵⁶,Netzband Nige¹,Tsang WaiFung¹⁷⁸,Weiss Brandon¹⁹,Gandy Sam¹,Cowley‐Court Tessa²³^ORCID,Halman Andreas³,McHerron Diana²,Jong Angelina⁷⁸,Kennedy Tom²^ORCID,White Eleanor²,Perkins Daniel²³¹⁰,Terhune Devin B.⁴,Sarris Jerome²¹¹¹²^ORCID

Affiliation:

1. Onaya Science Iquitos Peru

2. Psychae Institute Melbourne Victoria Australia

3. School of Population and Global Health University of Melbourne Melbourne Australia

4. Psychology and Psychotherapy department Central and North West London NHS Trust London UK

5. School of Medicine University of Yale New Haven Connecticut USA

6. Department of Psychology University of New Mexico Albuquerque New Mexico USA

7. Institute of Psychology, Psychiatry and Neuroscience South London and The Maudsley NHS Trust London UK

8. Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience King's College London London UK

9. Division of Psychiatry Imperial College London London UK

10. Centre for Mental Health Swinburne University Melbourne Australia

11. NICM Health Research Institute Western Sydney University Sydney Australia

12. Florey Institute for Neuroscience and Mental Health University of Melbourne Melbourne Australia

Abstract

AbstractAyahuasca is a psychedelic plant brew originating from the Amazon rainforest. It is formed from two basic components, the Banisteriopsis caapi vine and a plant containing the potent psychedelic dimethyltryptamine (DMT), usually Psychotria viridis. Here we review the history of ayahuasca and describe recent work on its pharmacology, phenomenological responses, and clinical applications. There has been a significant increase in interest in ayahuasca since the turn of the millennium. Anecdotal evidence varies significantly, ranging from evangelical accounts to horror stories involving physical and psychological harm. The effects of the brew on personality and mental health outcomes are discussed in this review. Furthermore, phenomenological analyses of the ayahuasca experience are explored. Ayahuasca is a promising psychedelic agent that warrants greater empirical attention regarding its basic neurochemical mechanisms of action and potential therapeutic application.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pcn5.146

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