Optimal sample sizes for phase II clinical trials and pilot studies
Author:
Affiliation:
1. Warwick Medical School; University of Warwick; UK
Publisher
Wiley
Subject
Statistics and Probability,Epidemiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/sim.4357/fullpdf
Reference21 articles.
1. Designing phase II studies in the context of a programme of clinical research;Whitehead;Biometrics,1985
2. Sample sizes for phase II and phase III clinical trials: an integrated approach;Whitehead;Statistics in Medicine,1986
3. Decision-theoretic designs for phase II clinical trials allowing for competing studies;Stallard;Biometrics,2003
4. Moving statistics beyond the individual clinical trial: applying decision science to optimize a clinical development plan;Julious;Pharmaceutical Statistics,2005
5. Optimal sample size for a series of pilot trials of new agents;Yao;Biometrics,1996
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