Inhibition of CaMKK2 Enhances Fracture Healing by Stimulating Indian Hedgehog Signaling and Accelerating Endochondral Ossification

Author:

Williams Justin N1,Kambrath Anuradha Valiya1,Patel Roshni B1,Kang Kyung Shin1,Mével Elsa1,Li Yong1,Cheng Ying‐Hua2,Pucylowski Austin J1,Hassert Mariah A3,Voor Michael J45,Kacena Melissa A16,Thompson William R7,Warden Stuart J17,Burr David B1,Allen Matthew R126,Robling Alexander G1,Sankar Uma1

Affiliation:

1. Department of Anatomy and Cell BiologyIndiana University School of MedicineIndianapolisINUSA

2. Department of MedicineIndiana University School of MedicineIndianapolisINUSA

3. Department of Molecular Microbiology and ImmunologySaint Louis University School of MedicineSt. LouisMOUSA

4. Department of Orthopaedic SurgeryUniversity of Louisville School of MedicineLouisvilleKYUSA

5. Department of BioengineeringUniversity of Louisville Speed School of EngineeringLouisvilleKYUSA

6. Department of Orthopaedic SurgeryIndiana University School of MedicineIndianapolisINUSA

7. Department of Physical TherapySchool of Health and Rehabilitation SciencesIndiana UniversityIndianapolisINUSA

Funder

U.S. Department of Defense

National Institutes of Health

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Reference66 articles.

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2. Incidence and Economic Burden of Osteoporosis-Related Fractures in the United States, 2005-2025

3. Orthopaedic war injuries: from combat casualty care to definitive treatment: a current review of clinical advances, basic science, and research opportunities;Covey DC;Instr Course Lect,2008

4. Diagnosis, treatment, and rehabilitation of stress fractures in the lower extremity in runners

5. Re‐evaluation of low intensity pulsed ultrasound in treatment of tibial fractures (TRUST): randomized clinical trial;Busse JW;BMJ,2016

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