A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis

Author:

Mayo Marlyn J.1,Pockros Paul J.2,Jones David3,Bowlus Christopher L.4ORCID,Levy Cynthia5,Patanwala Imran6,Bacon Bruce7,Luketic Velimir89,Vuppalanchi Raj10,Medendorp Sharon11,Dorenbaum Alejandro12,Kennedy Ciara13,Novak Patricia14,Gu Joan15,Apostol George16,Hirschfield Gideon M.17

Affiliation:

1. Digestive and Liver Diseases University of Texas Southwestern Medical Center Dallas TX

2. Scripps Clinic and Scripps Translational Science Institute La Jolla CA

3. Institute of Cellular Medicine Newcastle University Newcastle upon Tyne United Kingdom

4. Division of Gastroenterology and Hepatology University of California Davis School of Medicine Sacramento CA

5. Division of Hepatology University of Miami Miller School of Medicine Miami FL

6. Royal Liverpool University Hospital and University of Liverpool Liverpool United Kingdom

7. Division of Gastroenterology and Hepatology Saint Louis University School of Medicine St. Louis MO

8. Division of Gastroenterology, Hepatology and Nutrition Virginia Commonwealth University School of Medicine Richmond VA

9. McGuire Research Institute, McGuire VA Medical Center Richmond VA

10. Indiana University School of Medicine Indianapolis IN

11. Premier Research Research Triangle ParkNC

12. Stanford University Palo Alto CA

13. Amplyx Pharmaceuticals San Diego CA

14. Lumena Pharmaceuticals San Diego CA (one of the Shire group of companies)

15. Shire Lexington MA

16. Shire Zug Switzerland

17. Toronto Centre for Liver Disease University Health Network, University of Toronto Toronto Canada

Funder

Oxford PharmaGenesis

Shire International GmBH

Publisher

Wiley

Subject

General Medicine

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