Appendicitis in pregnant women: A systematic review and meta‐analysis of the diagnostic performance of ultrasonography

Abstract

AbstractObjectivesThe accuracy of ultrasound in the detection of appendicitis in pregnant women was examined in a meta‐analysis.MethodsPregnant women with suspected acute appendicitis were evaluated using ultrasound in a systematic search of PubMed, EMBASE, and Cochrane Library databases from January 1, 2011 to August 10, 2023. The sensitivity and specificity values and diagnostic odds ratios were obtained using the pooled data.ResultsA total of 239 patients were studied in four relevant investigations. Ultrasonography has a sensitivity of 56% and a specificity of 88% for the diagnosis of acute appendicitis, with an area under the receiver operating characteristic curve of 0.66%. Ultrasonography had a positive likelihood ratio of 4.65 (95% confidence interval, 1.42–15.23) and a negative likelihood ratio of 0.50 (95% confidence interval, 0.41–0.62). There was no evidence of publication bias (p = 0.93).ConclusionsUltrasound has moderate sensitivity for identifying appendicitis in pregnant women and may be utilized as an alternative diagnostic method.