Combination therapy with a T mprss6 RNA i‐therapeutic and the oral iron chelator deferiprone additively diminishes secondary iron overload in a mouse model of β‐thalassemia intermedia-Reference-Cited by-同舟云学术

Combination therapy with a T mprss6 RNA i‐therapeutic and the oral iron chelator deferiprone additively diminishes secondary iron overload in a mouse model of β‐thalassemia intermedia

Published:2015-03-23 Issue:4 Volume:90 Page:310-313
ISSN:0361-8609
Container-title:American Journal of Hematology
language:en
Short-container-title:Am. J. Hematol.

Author:

Schmidt Paul J.¹,Racie Tim²,Westerman Mark³,Fitzgerald Kevin²,Butler James S.²,Fleming Mark D.¹

Affiliation:

1. Department of PathologyBoston Children's Hospital and Harvard Medical SchoolBoston Massachusetts

2. Alnylam Pharmaceuticals, Inc.Cambridge Massachusetts

3. Intrinsic Lifesciences, Inc.LaJolla California

Funder

Alnylam Pharmaceuticals

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ajh.23934

Reference18 articles.

1. Hepcidin in iron overload disorders

2. Liver iron concentrations and urinary hepcidin in -thalassemia

3. A mouse model for beta 0-thalassemia.

4. Ineffective erythropoiesis in β-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

5. Liver expression of hepcidin and other iron genes in two mouse models of beta‐thalassemia;Franceschi L;Haematologica,2006

Cited by 68 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Content of medicine prescription and clinical practice training for haematology advanced practice nurses in China: A modified Delphi study;Nurse Education in Practice;2024-05

2. Combination of a TGF‐β ligand trap (RAP‐GRL) and TMPRSS6‐ASO is superior for correcting β‐thalassemia;American Journal of Hematology;2024-04-25

3. A human anti-matriptase-2 antibody limits iron overload, α-globin aggregates, and splenomegaly in β-thalassemic mice;Blood Advances;2024-04-11

4. Cellular and animal models for the investigation of β-thalassemia;Blood Cells, Molecules, and Diseases;2024-01

5. Iron chelation improves ineffective erythropoiesis and iron overload in myelodysplastic syndrome mice;eLife;2023-12-28