Quantification of DNA methylation and hydroxymethylation in Alzheimer's disease mouse model using LC-MS/MS

Author:

Huang Qionglin1,Xu Simin2,Mo Mingming1,Yang Qingjin1,Li Jian1,Zhong Yu1,Zhang Junjie1,Zhang Lijian1,Ye Xiaoxiao1,Liu Zhou2,Cai Chun1ORCID

Affiliation:

1. Analysis Center; Guangdong Medical University; Zhanjiang 524023 China

2. Institute of Neurology, Affiliated Hospital; Guangdong Medical University; Zhanjiang 524001 China

Funder

Doctoral Startup Project of Guangdong Natural Science Foundation

National Natural Science Foundation of China

Publisher

Wiley

Subject

Spectroscopy

Reference28 articles.

1. Mechanisms of Alzheimer's disease pathogenesis and prevention: the brain, neural pathology, N-methyl-D-aspartate receptors, tau protein and other risk factors;Kocahan;Clin Psychopharmaco lNeurosci,2017

2. Alzheimer's disease: pathological mechanisms and the beneficial role of melatonin;Rosales-Corral;J Pineal Res,2012

3. Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease;Aliev;Int J Biochem Cell Biol,2009

4. Epigenetic regulation in neurodevelopment and neurodegenerative diseases;Gapp;Neuroscience,2014

5. Epigenetic regulation in the pathophysiology of Alzheimer's disease;Chouliaras;Prog Neurobiol,2010

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