Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK‐448, for its anti‐tumor efficacy in a rat xenograft model-Reference-Cited by-同舟云学术

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Pharmacokinetic and pharmacodynamic modeling of the metastin/kisspeptin analog, TAK‐448, for its anti‐tumor efficacy in a rat xenograft model

Published:2020-07 Issue:7 Volume:41 Page:283-294
ISSN:0142-2782
Container-title:Biopharmaceutics & Drug Disposition
language:en
Short-container-title:Biopharm Drug Dispos

Author:

Kogame Akifumi¹^ORCID,Ishikawa Kaori²,DeJongh Joost³,Tagawa Yoshihiko¹,Matsui Hisanori⁴,Moriya Yuu¹^ORCID,Kondo Takahiro¹,Asahi Satoru¹

Affiliation:

1. Drug Metabolism and Pharmacokinetics Research LaboratoriesTakeda Pharmaceutical Company LimitedFujisawaKanagawaJapan

2. Oncology Drug Discovery UnitTakeda Pharmaceutical Company LimitedFujisawaKanagawaJapan

3. Leiden Experts on Advanced Pharmacokinetics & PharmacodynamicsLeidenthe Netherlands

4. XVGen Drug Discovery UnitPharmaceutical Research DivisionTakeda Pharmaceutical Company LimitedFujisawaKanagawaJapan

Funder

Takeda Pharmaceutical Company Limited

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science,Pharmacology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bdd.2245

Reference35 articles.

1. Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors

2. Pharmacokinetics/pharmacodynamics and the stages of drug development: Role of modeling and simulation

3. Comparison of four basic models of indirect pharmacodynamic responses

4. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54

5. Pharmacokinetic/pharmacodynamic modeling in drug research and development;Derendorf H.;The Journal of Clinical Pharmacology,2000

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