Intracellular CHO Cell Metabolite Profiling Reveals Steady-State Dependent Metabolic Fingerprints in Perfusion Culture-Reference-Cited by-同舟云学术

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Intracellular CHO Cell Metabolite Profiling Reveals Steady-State Dependent Metabolic Fingerprints in Perfusion Culture

Published:2017-03-03 Issue:4 Volume:33 Page:879-890
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnol Progress

Author:

Karst Daniel J.¹,Steinhoff Robert F.²,Kopp Marie R. G.¹,Serra Elisa¹,Soos Miroslav¹³,Zenobi Renato²,Morbidelli Massimo¹

Affiliation:

1. Dept. of Chemistry and Applied Biosciences; Inst. for Chemical and Bioengineering, ETH Zurich; Zurich Switzerland

2. Dept. of Chemistry and Applied Biosciences; Laboratory of Organic Chemistry, ETH Zurich; Zurich Switzerland

3. Dept. of Chemical Engineering; University of Chemistry and Technology; Prague 166 28 Czech Republic

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

Biotechnology

Reference36 articles.

1. Production of recombinant protein therapeutics in cultivated mammalian cells;Wurm;Nat Biotechnol.,2004

2. Maximizing productivity of CHO cell-based fed-batch culture using chemically defined media conditions and typical manufacturing equipment;Huang;Biotechnol Prog.,2010

3. Understanding the intracellular effect of enhanced nutrient feeding toward high titer antibody production process;Yu;Biotechnol Bioeng.,2011

4. Perfusion seed cultures improve biopharmaceutical fed-batch production capacity and product quality;Yang;Biotechnol Prog.,2014

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. WAVE-based intensified perfusion cell culture for fast process development;Biotechnology Letters;2023-06-29

2. Continuous Bioprocessing for Upstream Process: Perfusion Process;Cell Engineering;2023

3. Enablers of continuous processing of biotherapeutic products;Trends in Biotechnology;2022-07

4. Integrating metabolome dynamics and process data to guide cell line selection in biopharmaceutical process development;Metabolic Engineering;2022-07

5. Metabolic Profiling of CHO Cells during the Production of Biotherapeutics;Cells;2022-06-15

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