Radiosynthesis of a Bruton's tyrosine kinase inhibitor, [ 11 C]Tolebrutinib, via palladium‐NiXantphos‐mediated carbonylation-Reference-Cited by-同舟云学术

Radiosynthesis of a Bruton's tyrosine kinase inhibitor, [ 11 C]Tolebrutinib, via palladium‐NiXantphos‐mediated carbonylation

Published:2020-08-13 Issue:11 Volume:63 Page:482-487
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J Label Compd Radiopharm

Author:

Dahl Kenneth¹^ORCID,Turner Timothy²,Vasdev Neil¹^ORCID

Affiliation:

1. Azrieli Centre for Neuro‐Radiochemistry, Brain Health Imaging Centre, Centre for Addiction and Mental Health & Department of Psychiatry University of Toronto Ontario Canada

2. Sanofi MS/Neurology Sanofi Cambridge Massachusetts USA

Funder

Azrieli Foundation

Canada Foundation for Innovation

Canada Research Chairs

Ontario Research Foundation

Sanofi

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jlcr.3872

Reference24 articles.

1. Targeting Bruton's tyrosine kinase in B cell malignancies

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3. Specific peripheral B cell tolerance defects in patients with multiple sclerosis

4. Molecular imaging of multiple sclerosis: from the clinical demand to novel radiotracers

5. PRN2246, a potent and selective blood brain barrier penetrating BTK inhibitor, exhibits efficacy in central nervous system immunity;Francesco MR;Mult Scler J,2017

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