Insights into parent and adolescent patient understanding of genomic sequencing

Abstract

In a rapidly evolving genomics landscape, parents of children with cancer are asked to consider complex genetic concepts in order to make decisions about sequencing and comprehend the implications of results, all while facing a challenging diagnosis. To optimize parent and patient understanding, it is critical that the clinicians offering sequencing and disclosing results are aware of patient and family expectations and sufficiently educate them about the processes, procedures, and potential outcomes of paired tumor–germline sequencing.