Arginase‐II promotes melanoma migration and adhesion through enhancing hydrogen peroxide production and STAT3 signaling

Author:

Yu Yi12ORCID,Ladeiras Diogo1,Xiong Yuyan12ORCID,Boligan Kayluz Frias3,Liang Xiujie1,Gunten Stephan3,Hunger Robert E.4,Ming Xiu‐Fen1ORCID,Yang Zhihong1ORCID

Affiliation:

1. Laboratory of Cardiovascular and Aging Research, Department of Endocrinology, Faculty of Science and Medicine, Medicine Section, Metabolism and Cardiovascular Medicine University of Fribourg Fribourg Switzerland

2. Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, School of Medicine Northwest University Xi'an Shaanxi China

3. Institute of Pharmacology University of Bern Bern Switzerland

4. Department of Dermatology Bern University Hospital Inselspital, University of Bern Bern Switzerland

Funder

Schweizerische Herzstiftung

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

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1. Pathophysiology of Arginases in Cancer and Efforts in Their Pharmacological Inhibition;International Journal of Molecular Sciences;2024-09-10

2. Targeting the glutamine-arginine-proline metabolism axis in cancer;Journal of Enzyme Inhibition and Medicinal Chemistry;2024-07-25

3. Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion;European Journal of Medicinal Chemistry;2024-01

4. A Structure-function Analysis of Hepatocyte Arginase 2 Reveals Mitochondrial Ureahydrolysis as a Determinant of Glucose Oxidation;Cellular and Molecular Gastroenterology and Hepatology;2024

5. Amino acid metabolism in health and disease;Signal Transduction and Targeted Therapy;2023-09-13

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