CISD2 enhances the chemosensitivity of gastric cancer through the enhancement of 5-FU-induced apoptosis and the inhibition of autophagy by AKT/mTOR pathway

Author:

Sun Yi123ORCID,Jiang Yingming123,Huang Jintuan123,Chen Hao123,Liao Yi12,Yang Zuli12

Affiliation:

1. Department of Gastrointestinal Surgery; The Sixth Affiliated Hospital (Guangdong Gastrointestinal and Anal Hospital); Sun Yat-Sen University; Guangzhou China

2. Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases; The Sixth Affiliated Hospital; Sun Yat-sen University; Guangzhou China

3. Guangdong Institute of Gastroenterology; Guangzhou China

Funder

National Key Clinical Discipline

Science and Technology Planning Project of Guangdong Province

Natural Science Foundation of Guangdong Province

Publisher

Wiley

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Reference35 articles.

1. WHO http://www.who.int/mediacentre/factsheets/fs297/en/ Cancer fact sheet

2. Cancer statistics in China, 2015;Chen;CA Cancer J. Clin.,2016

3. Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine;Sakuramoto;N. Engl. J. Med.,2007

4. Chemotherapy for metastatic disease: review from JCOG trials;Boku;Int. J. Clin. Oncol.,2008

5. Oxaliplatin, 5fluorouracil and leucovorin (FOLFOX4) as first line chemotherapy in elderly patients with advanced gastric cancer;Haghighi;Asian Pac. J. Cancer Prev.,2016

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