A patient with oligometastatic hormone‐sensitive prostate cancer who achieved long‐term progression‐free survival following cytoreductive radical prostatectomy and metastasectomy

Author:

Mamiya Daisuke1,Kijima Toshiki1ORCID,Takada‐Owada Atsuko2,Kokubun Hidetoshi1,Uematsu Toshitaka1,Takei Kohei1,Kambara Tsunehito3,Ishida Kazuyuki2,Taneichi Hiroshi4,Kamai Takao1ORCID

Affiliation:

1. Department of Urology Dokkyo Medical University Shimotsuga Tochigi Japan

2. Department of Diagnostic Pathology Dokkyo Medical University Shimotsuga Tochigi Japan

3. Department of Urology Nasu Red Cross Hospital Otawara Tochigi Japan

4. Department of Orthopaedic Surgery Dokkyo Medical University Shimotsuga Tochigi Japan

Abstract

IntroductionOligometastatic prostate cancer can be well‐controlled through combined local and metastasis‐directed therapies. However, the effects of cytoreductive radical prostatectomy and metastasectomy remain unclear.Case presentationA 52‐year‐old man presented with prostate cancer and isolated bone metastasis to the thoracic spine. Six months after neoadjuvant hormonal therapy, the patient underwent cytoreductive radical prostatectomy and total en bloc spondylectomy. The postoperative course was uneventful. Hormonal therapy was terminated 5 years after surgery, and no biochemical or radiological progression was observed at 7 years postoperatively.ConclusionAlthough careful patient selection is necessary, cytoreductive radical prostatectomy and metastasectomy are effective treatments for well‐selected patients with oligometastatic prostate cancer.

Publisher

Wiley

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