A case of condyloma acuminatum of the bladder concurrently diagnosed with urothelial carcinoma

Author:

Tsuru Ibuki1ORCID,Nakamura Masaki1ORCID,Izumi Taro1ORCID,Ono Akihiro1,Miura Sakiko2,Morikawa Teppei2,Shigehara Kazuyoshi3,Kitamura Tadaichi4,Kume Haruki5ORCID,Shiga Yoshiyuki1

Affiliation:

1. Department of Urology NTT Medical Center Tokyo Tokyo Japan

2. Department of Diagnostic Pathology NTT Medical Center Tokyo Tokyo Japan

3. Department of Integrative Cancer Therapy and Urology Kanazawa University Graduate School of Medical Science Kanazawa Japan

4. Japanese Foundation for Sexual Health Medicine Tokyo Japan

5. Department of Urology The University of Tokyo hospital Tokyo Japan

Abstract

IntroductionCondyloma acuminatum usually occurs in the external genitalia and rarely in the bladder mucosa. Here, we report a case of condyloma acuminatum of the bladder that was detected concurrently with urothelial carcinoma.Case presentationA 42‐year‐old man was referred to our urology department with positive urine cytology for urothelial carcinoma. Cystoscopy revealed a broad‐base nonpapillary bladder tumor. The patient underwent a transurethral resection of the bladder tumor. Pathological examination revealed urothelial carcinoma, high‐grade pT1, and concurrent resection of condyloma acuminatum. DNA was extracted from the paraffin‐embedded transurethral resection of the bladder tumor tissue specimens. HPV11 was detected in condylomas by PCR and in situ hybridization, whereas HPV was not detected in urothelial carcinomas.ConclusionWe report a rare case of condyloma acuminatum of the bladder that was concurrently diagnosed with urothelial carcinoma from the same site.

Publisher

Wiley

Subject

Urology

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