Clinical validity of aDPYD-based pharmacogenetic test to predict severe toxicity to fluoropyrimidines

Author:

Toffoli Giuseppe1,Giodini Luciana1,Buonadonna Angela2,Berretta Massimiliano3,De Paoli Antonino4,Scalone Simona2,Miolo Gianmaria2,Mini Enrico5,Nobili Stefania6,Lonardi Sara7,Pella Nicoletta8,Lo Re Giovanni9,Montico Marcella1,Roncato Rossana1,Dreussi Eva1,Gagno Sara1,Cecchin Erika1

Affiliation:

1. Experimental and Clinical Pharmacology; Centro Di Riferimento Oncologico-National Cancer Institute; 2-33081 Aviano Italy

2. Medical Oncology Unit B; Centro Di Riferimento Oncologico-National Cancer Institute; 2-33081 Aviano Italy

3. Medical Oncology Unit A; Centro Di Riferimento Oncologico-National Cancer Institute; 2-33081 Aviano Italy

4. Department of Radiation Oncology; Centro Di Riferimento Oncologico-National Cancer Institute; 2-33081 Aviano Italy

5. Section of Internal Medicine; Department of Experimental and Clinical Medicine; University of Florence; 6-50139 Florence Italy

6. Section of Clinical Pharmacology and Oncology; Department of Health Sciences; University of Florence; 6-50139 Florence Italy

7. Medical Oncology Unit 1; Istituto Oncologico Veneto- IRCCS; 64-35128 Padua Italy

8. Medical Oncology Unit; University Hospital; 15-33100 Udine Italy

9. Oncology Unit; “Azienda Ospedaliera Santa Maria degli Angeli”; Pordenone Italy

Funder

“Associazione Italiana per la Ricerca sul Cancro” (AIRC) [Special Program Molecular Clinical Oncology, 5x1000]

Publisher

Wiley

Subject

Cancer Research,Oncology

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