Affiliation:
1. Department of Chemistry Indian Institute of Technology Roorkee Roorkee 247667, Uttarakhand India
2. Biophysical and Computational Chemistry Laboratory, Department of Chemistry National Institute of Technology Karnataka Surathkal, Mangalore 575025 India
Abstract
AbstractConformation of biomolecules like DNA, peptides and amino acids play vital role during nanoparticle growth. Herein, we have experimentally explored the effect of different noncovalent interaction between a 5′‐amine modified DNA sequence (NH2−C6H12‐5′‐ACATCAGT‐3′, PMR) and arginine during the seed‐mediated growth reaction of gold nanorods (GNRs). Amino acid‐mediated growth reaction of GNRs results in a snowflake‐like gold nanoarchitecture. However, in case of Arg, prior incubation of GNRs with PMR selectively produces sea urchin‐like gold suprastructures, via strong hydrogen bonding and cation‐π interaction between PMR and Arg. This distinctive structure formation strategy has been extended to study the structural modulation caused by two structurally close α‐helical RRR (Ac‐(AAAAR)3A−NH2) peptide and the lysine mutated KKR (Ac−AAAAKAAAAKAAAARA−NH2) peptide with partial helix at the amino terminus. Simulation studies confirm that a greater number of hydrogen bonding and cation‐π interaction between the Arg residues and PMR resulted in the gold sea urchin structure for RRR peptide against KKR peptide.
Subject
General Chemistry,Biochemistry,Organic Chemistry
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献