Rational Design, Synthesis and Evaluation of Oxazolo[4,5‐ c ]‐quinolinone Analogs as Novel Interleukin‐33 Inhibitors-Reference-Cited by-同舟云学术

Rational Design, Synthesis and Evaluation of Oxazolo[4,5‐ c ]‐quinolinone Analogs as Novel Interleukin‐33 Inhibitors

Published:2021-09-28 Issue:22 Volume:16 Page:3702-3712
ISSN:1861-4728
Container-title:Chemistry – An Asian Journal
language:en
Short-container-title:Chem. Asian J.

Author:

Kim Yujin¹,Ma Chao¹²,Park Seonghu¹,Shin ‐ Yujin¹,Lee Taeyun¹,Paek Jiwon¹,Hoon Kim Kyong³,Jang Geonhee¹,Cho Haelim⁴,Son Seyoung⁵,Son Sang‐Hyun⁵,Yong Lee Ki¹,Lee Kiho¹,Woo Jung Yong¹,Ho Jeon Young¹,Byun Youngjoo¹

Affiliation:

1. College of Pharmacy Korea University 2511 Sejong-ro Sejong 30019 South Korea

2. Current address College of Food & Pharmaceutical Engineering Guizhou Institute of Technology Guizhou 550003 P. R. China

3. Department of Biotechnology and Bioinformatics Korea University Sejong 30019 South Korea

4. T&J TECH Inc. 212 Gasan digital 1-ro, Geumcheon-gu Seoul 08502 South Korea

5. Azcuris, Co., Ltd. 2511 Sejong-ro Sejong 30019 South Korea

Publisher

Wiley

Subject

General Chemistry,Biochemistry,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/asia.202100896

Reference45 articles.

2. IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

3. Endogenous IL-33 Is Highly Expressed in Mouse Epithelial Barrier Tissues, Lymphoid Organs, Brain, Embryos, and Inflamed Tissues: In Situ Analysis Using a Novel Il-33–LacZ Gene Trap Reporter Strain

4. The Danger Signal, Extracellular ATP, Is a Sensor for an Airborne Allergen and Triggers IL-33 Release and Innate Th2-Type Responses

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