Affiliation:
1. Engineering Research Center of Pharmaceutical Process Chemistry Ministry of Education East China University of Science and Technology 130 Meilong Road Shanghai 200237 China
Abstract
AbstractTransition‐mental‐free multi‐component hydroxysulfenylation of styrenes with NH4SCN and water to from β‐hydroxysulfides is established. The reaction mechanism proceeded via a domino reaction after a radical addition to 2‐phenylimidazo[1,2‐a]pyridines. This approach features a wide substrate scope and functional group compatibility, providing 34 compounds in acceptable yields.
Funder
National Natural Science Foundation of China
Subject
General Chemistry,Biochemistry,Organic Chemistry