The relationship between fermented and nonfermented dairy products consumption and hypertension among premature coronary artery disease patients: Iran premature coronary artery disease study

Author:

Ansari Shakila1ORCID,Mohammadifard Noushin2,Hajihashemi Parisa3ORCID,Haghighatdoost Fahimeh4ORCID,Zarepur Ehsan25,Mahmoudi Shirin4,Nouri Fatemeh4,Nouhi Fereydoon67,Kazemi Tooba8,Salehi Nahid9,Solati Kamal10,Ghaffari Samad11,Gholipour Mahboobeh12,Dehghani Mostafa13,Cheraghi Mostafa13,Heybar Habib14,Alikhasi Hassan15,Sarrafzadegan Nizal416

Affiliation:

1. Department of Community Nutrition, Nutrition and Food Security Research Center, School of Nutrition and Food Science Isfahan University of Medical Sciences Isfahan Iran

2. Interventional Cardiology Research Center, Cardiovascular Research Institute Isfahan University of Medical Sciences Isfahan Iran

3. Isfahan Gastroenterology and Hepatology Research Center Isfahan University of Medical Sciences Isfahan Iran

4. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute Isfahan University of Medical Sciences Isfahan Iran

5. Department of Cardiology, Medicine School Isfahan University of Medical Sciences Isfahan Iran

6. Rajaie Cardiovascular Medical and Research Center Iran University of Medical Sciences Tehran Iran

7. Iranian Network of Cardiovascular Research (INCVR) Tehran Iran

8. Cardiovascular Diseases Research Center Birjand University of Medical Sciences Birjand Iran

9. Cardiovascular Research Center, Health Institute Kermanshah University of Medical Sciences Kermanshah Iran

10. Department of Psychiatry Shahrekord University of Medical Sciences Shahrekord Iran

11. Cardiovascular Research Center Tabriz University of Medical sciences Tabriz Iran

12. Department of Cardiology, Healthy Heart Research Center, Heshmat Hospital, School of Medicine Guilan University of Medical Sciences Rasht Iran

13. Department of Cardiovascular Research Center, Shahid Rahimi Hospital Lorestan University of Medical Sciences Khorramabad Iran

14. Atherosclerosis Research Center Ahvaz Jundishapur University of Medical Sciences Ahvaz Iran

15. Heart Failure Research Center, Cardiovascular Research Institute Isfahan University of Medical Sciences Isfahan Iran

16. Faculty of Medicine, School of Population and Public Health University of British Columbia Vancouver Canada

Abstract

AbstractDairy products may affect hypertension (HTN) risk. The aim of this study was to examine the association between fermented and nonfermented dairy foods and HTN in a sample of premature coronary artery disease (PCAD) subjects. This cross‐sectional study was performed on 1854 PCAD patients. A 110‐item food frequency questionnaire was used to assess dietary intakes. HTN was considered if systolic blood pressure was 140 mmHg and higher and/or diastolic blood pressure was 90 mmHg and higher. The odds ratio of HTN across the quartiles of different types of dairy products was evaluated by binary logistic regression. The mean (SD) of dairy products consumption was 339.8 (223.5) g/day, of which 285.4 g/day was fermented dairy products. In the crude model, participants in the fourth quartile of fermented dairy products had lesser risk of HTN compared to the bottom quartile (OR = 0.70, 95% CI: 0.52, 0.96; p for trend = .058). However, after considering the possible confounders, the significance disappeared. Subjects in the top quartile of high‐fat fermented dairy products had 34% lower risk for HTN compared to the bottom quartile (95% CI: 0.49, 0.88; p for trend < .001). Adjustment for potential risk factors weakened the association but remained significant (OR = 0.73, 95% CI: 0.53, 1.01; p for trend = .001). Nonsignificant relation was detected between low‐fat fermented, low‐fat nonfermented, and high‐fat nonfermented dairy products and HTN. Moderate consumption of high‐fat fermented dairy products, in a population with low consumption of dairy foods, might relate to reduced likelihood of HTN.

Funder

Isfahan University of Medical Sciences

Publisher

Wiley

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