Microtransplantation of whole ganglionic eminence cells ameliorates motor deficit, enlarges the volume of grafts, and prolongs survival in a rat model of Huntington's disease
Author:
Affiliation:
1. Department of Neurosurgery; Tongji Hospital; Tongji Medical College; Huazhong University of Science and Technology; Wuhan China
2. Department of Immunology; Johns Hopkins University School of Medicine; Baltimore Maryland
Funder
National Natural Science Foundation of China
Natural Science Foundation of Hubei Province
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jnr.23282/fullpdf
Reference33 articles.
1. Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: a long-term follow-up study;Bachoud-Levi;Lancet Neurol,2006
2. Immune problems in central nervous system cell therapy;Barker;Neurotherapeutics,2004
3. Functional improvement with low-dose dopaminergic grafts in hemiparkinsonian rats;Bartlett;Neurosurgery,2004
4. Cellular therapy and induced neuronal replacement for Huntington's disease;Benraiss;Neurotherapeutics,2011
5. Time-dependent expression of donor- and host-specific major histocompatibility complex class I and II antigens in allogeneic dopamine-rich macro- and micrografts: comparison of two different grafting protocols;Brandis;Acta Neuropathol,1998
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