Affiliation:
1. Center for AIE Research, College of Materials Science and Engineering Shenzhen University Shenzhen China
2. Department of Chemistry, Key Laboratory of Nanobiosensing and Nanobioanalysis at Universities of Jilin Province Northeast Normal University Changchun China
3. School of Science and Engineering, Shenzhen Institute of Molecular Aggregate Science and Engineering The Chinese University of Hong Kong Shenzhen China
Abstract
AbstractIn the past 5 years, aggregation‐induced emission luminogens (AIEgens) with emission in the second near‐infrared (NIR‐II) optical window have aroused great interest in bioimaging and disease phototheranostics, benefiting from the merits of deep penetration depth, reduced light scatting, high spatial resolution, and minimal photodamage. To construct NIR‐II AIEgens, thiophene derivatives are frequently adopted as π‐bridge by virtue of their electron‐rich feature and good modifiability. Herein, we summarize the recent progress of NIR‐II AIEgens by employing thiophene derivatives as π‐bridge mainly compassing unsubstituted thiophene, alkyl thiophene, 3,4‐ethylenedioxythiophene, and benzo[c]thiophene, with a discussion on their structure–property relationships and biomedical applications. Finally, a brief conclusion and perspective on this fascinating area are offered.
Funder
National Natural Science Foundation of China
Shenzhen Science and Technology Innovation Program
Guangdong Provincial Pearl River Talents Program
Science Fund for Distinguished Young Scholars of Guangdong Province
Basic and Applied Basic Research Foundation of Guangdong Province
Subject
Chemistry (miscellaneous),Biophysics