Tailored and universal parallel transmit broadband pulses for homogeneous 3D excitation of the human heart at 7T

Author:

Aigner Christoph Stefan1ORCID,Dietrich‐Conzelmann Sebastian1ORCID,Lutz Max1ORCID,Krüger Felix1ORCID,Schmitter Sebastian123ORCID

Affiliation:

1. Physikalisch‐Technische Bundesanstalt (PTB) Braunschweig and Berlin Germany

2. University of Minnesota Center for Magnetic Resonance Research Minneapolis Minnesota USA

3. Medical Physics in Radiology German Cancer Research Center (DKFZ) Heidelberg Germany

Abstract

AbstractPurposeTo research and evaluate the performance of broadband tailored kT‐point pulses (TP) and universal pulses (UP) for homogeneous excitation of the human heart at 7T.MethodsRelative 3D ‐maps of the thorax were acquired from 29 healthy volunteers. TP and UP were designed using the small‐tip‐angle approximation for a different composition of up to seven resonance frequencies. TP were computed for each of the 29 ‐maps, and UPs were calculated using 22 ‐maps and tested in seven testcases. The performance of the pulses was analyzed using the coefficient of variation (CV) in the 3D heart volumes. The 3D gradient‐echo (GRE) scans were acquired for the seven testcases to qualitatively validate the ‐predictions.ResultsSingle‐ and double‐frequency optimized pulses achieved homogeneity in flip angle (FA) for the frequencies they were optimized for, while the broadband pulses achieved uniformity in FA across a 1300 Hz frequency range.ConclusionBroadband TP and UP can be used for homogeneous excitation of the heart volume across a 1300 Hz frequency range, including the water and the main six fat peaks, or with longer pulse durations and higher FAs for a smaller transmit bandwidth. Moreover, despite large inter‐volunteer variations, broadband UP can be used for calibration‐free 3D heart FA homogenization in time‐critical situations.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

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