A Novel Long-Acting Human Growth Hormone Fusion Protein (VRS-317): Enhanced In Vivo Potency and Half-Life

Author:

Cleland Jeffrey L.,Geething Nathan C.,Moore Jerome A.,Rogers Brian C.,Spink Benjamin J.,Wang Chai-Wei,Alters Susan E.,Stemmer Willem P.C.,Schellenberger Volker

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference19 articles.

1. Compliance and persistence in pediatric and adult patients receiving growth hormone therapy;Rosenfeld;Endocr Pract,2008

2. Pulsatile versus continuous intravenous administration of growth hormone (GH) in GH-deficient patients: Effects on circulating insulin-like growth factor-I and metabolic indices;Jørgensen;J Clin Endocrinol Metab,1990

3. Continuous infusion versus daily injections of growth hormone (GH) for 4weeks in GH-deficient patients;Laursen;J Clin Endocrinol Metab,1995

4. Differential regulation of serum growth hormone (GH)-binding protein during continuous infusion versus daily injection of recombinant human GH in GH-deficient children;Tauber;J Clin Endocrinol Metab,1993

5. Long-term effects of continuous subcutaneous infusion versus daily subcutaneous injections of growth hormone (GH) on the insulin-like growth factor system, insulin sensitivity, body composition, and bone and lipoprotein metabolism in GH-deficient adults;Laursen;J Clin Endocrinol Metab,2001

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