Affiliation:
1. Department of Internal Medicine Reproduction, and Population Medicine, Faculty of Veterinary Medicine, Ghent University Merelbeke Belgium
2. Federal Agency for the Safety of the Food Chain Brussels Belgium
3. Animal Health Services Flanders (DGZ Vlaanderen) Torhout Belgium
Abstract
AbstractBackgroundAnaplasma phagocytophilum is a tick‐borne zoonotic bacterium that is the aetiologic pathogen of tick‐borne fever (TBF) in ruminants. In clinical bovine cases of TBF, abortion and stillbirth may be observed. However, in this regard, the pathophysiology of TBF has not yet been completely elucidated, and no clear guidelines to diagnose A. phagocytophilum‐related abortions and perinatal mortalities (APM) are available.MethodsThis exploratory study aimed to investigate the presence of A. phagocytophilum in bovine cases of APM and determine whether placental or fetal spleen tissue has the greatest sensitivity for A. phagocytophilum identification. The placenta and fetal spleen of 150 late‐term bovine APM cases were analysed using real‐time PCR to detect A. phagocytophilum.ResultsA total of 2.7% of sampled placentas were positive for A. phagocytophilum, while none of the fetal spleen samples was.LimitationsNo histopathology to detect associated lesions was performed. Consequently, no evidence of causality between the detection of A. phagocytophilum and APM events could be achieved.ConclusionThe detection of A. phagocytophilum suggests a potential role of this pathogen in bovine APM, and placental tissue seems to be the most suitable tissue for its identification.
Funder
Federaal Agentschap Voor de Veiligheid Van de Voedselketen
Subject
General Veterinary,General Medicine
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献