Efficient generation of osteoclasts from human induced pluripotent stem cells and functional investigations of lethal CLCN7 ‐related osteopetrosis

Author:

Rössler Uta123ORCID,Hennig Anna Floriane1245ORCID,Stelzer Nina12,Bose Shroddha6,Kopp Johannes1247ORCID,Søe Kent8910ORCID,Cyganek Lukas1112ORCID,Zifarelli Giovanni13ORCID,Ali Salaheddine127ORCID,Hagen Maja14ORCID,Strässler Elisabeth Tamara1516ORCID,Hahn Gabriele17,Pusch Michael13ORCID,Stauber Tobias618ORCID,Izsvák Zsuzsanna19ORCID,Gossen Manfred2021ORCID,Stachelscheid Harald2223ORCID,Kornak Uwe1257ORCID

Affiliation:

1. BIH Center for Regenerative Therapies (BCRT) Charité ‐ Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt‐Universität zu Berlin, and Berlin Institute of Health Berlin Germany

2. Institute for Medical Genetics and Human Genetics Charité ‐ Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt‐Universität zu Berlin, and Berlin Institute of Health Berlin Germany

3. Berlin Institute of Health (BIH) Berlin Germany

4. Freie Universität Berlin Berlin Germany

5. Institute of Human Genetics University Medical Center Göttingen Göttingen Germany

6. Institute of Chemistry and Biochemistry Freie Universität Berlin Berlin Germany

7. Max Planck Institute for Molecular Genetics Berlin Germany

8. Clinical Cell Biology, Department of Pathology Odense University Hospital Odense C Denmark

9. Department of Clinical Research University of Southern Denmark Odense M Denmark

10. Department of Molecular Medicine University of Southern Denmark Odense M Denmark

11. Stem Cell Unit, Clinic for Cardiology and Pneumology University Medical Center Göttingen Göttingen Germany

12. German Center for Cardiovascular Research (DZHK) Partner Site Göttingen Göttingen Germany

13. Istituto di Biofisica, CNR Genoa Italy

14. Abteilung Neuropädiatrie, Medizinische Fakultät Carl Gustav Carus Technische Universität Dresden Dresden Germany

15. Department of Cardiology Charité ‐ Universitätsmedizin Berlin, Campus Benjamin Franklin Berlin Germany

16. German Centre for Cardiovascular Research (DZHK) Partner Site Berlin Berlin Germany

17. Institut und Poliklinik für Radiologische Diagnostik Medizinische Fakultät Carl Gustav Carus Technische Universität Dresden Dresden Germany

18. Department of Human Medicine, and Institute for Molecular Medicine MSH Medical School Hamburg Hamburg Germany

19. Max‐Delbrück‐Center for Molecular Medicine (MDC), Helmholtz Association Berlin Germany

20. Berlin‐Brandenburg Center for Regenerative Therapies Charité Virchow Campus Berlin Germany

21. Institute of Active Polymers Helmholtz‐Zentrum Hereon Teltow Germany

22. Charité ‐ Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt‐Universität zu Berlin, and Berlin Institute of Health Berlin Germany

23. Berlin Institute of Health (BIH) BIH Stem Cell Core Facility Berlin Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

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