Assessment of pharmacokinetics, bioavailability and protein binding of anacetrapib in rats by a simple high-performance liquid chromatography-tandem mass spectrometry method-Reference-Cited by-同舟云学术

Assessment of pharmacokinetics, bioavailability and protein binding of anacetrapib in rats by a simple high-performance liquid chromatography-tandem mass spectrometry method

Published:2016-08-08 Issue:2 Volume:31 Page:e3791
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomed. Chromatogr.

Author:

Kim Sang-Bum¹,Kim Ki Taek²,Joo Jeongmin¹,Seo Kyung-Ah¹,Hwang Hayoung¹,Kim Soong-Hyun¹,Song Minsoo¹,Lee Sungwoo¹,Jahn Alexander³,Cho Hyun-Jong⁴,Kim Dae-Duk²,Yoon In-Soo⁵

Affiliation:

1. New Drug Development Center; Daegu-Gyeongbuk Medical Innovation Foundation; Daegu 41061 Republic of Korea

2. College of Pharmacy and Research Institute of Pharmaceutical Sciences; Seoul National University; Seoul 08826 Republic of Korea

3. Department of Biotechnology; Dongseo University; Busan 47011 Republic of Korea

4. College of Pharmacy; Kangwon National University; Gangwon 24341 Republic of Korea

5. College of Pharmacy and Natural Medicine Research Institute; Mokpo National University; Jeonnam 58554 Republic of Korea

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/bmc.3791/fullpdf

Reference21 articles.

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2. Quantitation of anacetrapib, stable-isotope labeled-anacetrapib (microdose), and four metabolites in human plasma using liquid chromatography tandem mass spectrometry. Journal of Chromatography B: Analytical Technology in Biomedicine and;Chavez-Eng;Life Sciences,2016

3. Plasma protein binding and pharmacological response;Souich;Clinical Pharmacokinetics,1993

4. Lipids, safety parameters, and drug concentrations after an additional 2 years of treatment with anacetrapib in the DEFINE study;Gotto;Journal of Cardiovascular Pharmacology and Therapeutics,2014

5. Inhibition of cholesteryl ester transfer protein by anacetrapib does not impair the anti-inflammatory properties of high density lipoprotein;Han;Biochimica Biophysica Acta,2013

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