Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses

Author:

Kim Soon‐Chan1234ORCID,Park Ji Won356,Seo Ha‐Young13ORCID,Kim Minjung356,Park Jae‐Hyeon13,Kim Ga‐Hye123ORCID,Lee Ja Oh13,Shin Young‐Kyoung134,Bae Jeong Mo7,Koo Bon‐Kyoung8,Jeong Seung‐Yong356ORCID,Ku Ja‐Lok1234ORCID

Affiliation:

1. Korean Cell Line Bank Laboratory of Cell Biology Cancer Research Institute Seoul National University College of Medicine Seoul 03080 South Korea

2. Department of Biomedical Sciences Seoul National University College of Medicine Seoul 03080 South Korea

3. Cancer Research Institute Seoul National University Seoul 03080 South Korea

4. Ischemic/Hypoxic Disease Institute Seoul National University College of Medicine Seoul 03080 South Korea

5. Department of Surgery Seoul National University College of Medicine Seoul 03080 South Korea

6. Division of Colorectal Surgery Department of Surgery Seoul National University Hospital Seoul 03080 South Korea

7. Department of Pathology Seoul National University College of Medicine Seoul 03080 South Korea

8. Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) Vienna Biocenter (VBC) Dr. Bohr‐Gasse 3 Vienna 1030 Austria

Funder

Seoul National University Hospital

National Research Foundation of Korea

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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