Reversible Treatment of Pressure Overload‐Induced Left Ventricular Hypertrophy through Drd5 Nucleic Acid Delivery Mediated by Functional Polyaminoglycoside

Author:

Jiang Xiaoliang1,Shao Meiyu2,Liu Xue1,Liu Xing1,Zhang Xu3,Wang Yuming3,Yin Kunlun4,Wang Shuiyun5,Hu Yang2,Jose Pedro A67,Zhou Zhou4,Xu Fu‐Jian2,Yang Zhiwei1ORCID

Affiliation:

1. NHC Key Laboratory of Human Disease Comparative Medicine (The Institute of Laboratory Animal Sciences, CAMS & PUMC), and Beijing Engineering Research Center for Experimental Animal Models of Human Critical Diseases 5 Pan Jia Yuan Nan Li, Chaoyang District Beijing 100021 P. R. China

2. Key Lab of Biomedical Materials of Natural Macromolecules Ministry of Education Beijing Laboratory of Biomedical Materials Beijing Advanced Innovation Center for Soft Matter Science and Engineering Beijing University of Chemical Technology Beijing 100029 P. R. China

3. Department of Hepato‐Biliary‐Pancreatic Surgery Henan Provincial People's Hospital People's Hospital of Zhengzhou University Zhengzhou Henan 450003 P. R. China

4. State Key Laboratory of Cardiovascular Disease Beijing Key Laboratory for Molecular Diagnostics of Cardiovascular Diseases Diagnostic Laboratory Service Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 P. R. China

5. Department of Cardiovascular Surgery State Key Laboratory of Cardiovascular Disease Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100037 P. R. China

6. Department of Pharmacology and Physiology The George Washington University School of Medicine & Health Sciences Washington DC 20052 USA

7. Department of Medicine Division of Kidney Diseases & Hypertension The George Washington University School of Medicine & Health Sciences Washington DC 20052 USA

Funder

Fundamental Research Funds for the Central Universities

Foundation for the National Institutes of Health

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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