Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes

Author:

Zhang Jing1,Ni Yueqiong23,Qian Lingling1,Fang Qichen1,Zheng Tingting23,Zhang Mingliang1,Gao Qiongmei1,Zhang Ying1,Ni Jiacheng1,Hou Xuhong1,Bao Yuqian1,Kovatcheva‐Datchary Petia4,Xu Aimin56,Li Huating1,Panagiotou Gianni2356,Jia Weiping1ORCID

Affiliation:

1. Shanghai Key Laboratory of Diabetes Mellitus Department of Endocrinology and Metabolism Shanghai Diabetes Institute Shanghai Clinical Center for Diabetes Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233 China

2. Systems Biology and Bioinformatics Unit Leibniz Institute for Natural Product Research and Infection Biology–Hans Knöll Institute Beutenbergstrasse 11a Jena 07745 Germany

3. Systems Biology & Bioinformatics Group School of Biological Sciences The University of Hong Kong Hong Kong SAR China

4. Institute for Molecular Infection Biology University of Wurzburg Wurzburg D‐97080 Germany

5. State Key Laboratory of Pharmaceutical Biotechnology The University of Hong Kong Hong Kong SAR China

6. Department of Medicine The University of Hong Kong Hong Kong SAR China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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