RNF126‐Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple‐Negative Breast Cancer to Radiotherapy

Author:

Liu Wenjing123,Zheng Min12,Zhang Rou1,Jiang Qiuyun12,Du Guangshi12,Wu Yingying4,Yang Chuanyu12,Li Fubing5,Li Wei12,Wang Luzhen16,Wu Jiao3,Shi Lei7,Li Wenhui3,Zhang Kai7,Zhou Zhongmei1,Liu Rong18,Gao Yingzheng9,Huang Xinwei9,Fan Songqing10,Zhi Xu11ORCID,Jiang Dewei12ORCID,Chen Ceshi135ORCID

Affiliation:

1. Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province Kunming Institute of Zoology Chinese Academy of Sciences Kunming 650201 China

2. Kunming College of Life Sciences University of the Chinese Academy of Sciences Kunming 650204 China

3. The Third Affiliated Hospital Kunming Medical University Kunming 650118 China

4. Department of the Pathology First Affiliated Hospital of Kunming Medical University Kunming 650032 China

5. Academy of Biomedical Engineering Kunming Medical University Kunming 650500 China

6. School of Life Science University of Science & Technology of China Hefei 230027 China

7. Department of Biochemistry and Molecular Biology Tianjin Medical University Tianjin 300070 China

8. Translational Cancer Research Center Peking University First Hospital Beijing 100034 China

9. Department of the Central Laboratory Second Affiliated Hospital of Kunming Medical University Kunming 650032 China

10. Department of Pathology the Second Xiangya Hospital Central South University Changsha 410000 China

11. Center for Reproductive Medicine Department of Obstetrics and Gynecology Peking University Third Hospital Beijing 100191 China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Beijing Municipality

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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