Trip13 Depletion in Liver Cancer Induces a Lipogenic Response Contributing to Plin2‐Dependent Mitotic Cell Death

Author:

Rios Garcia Marcos1234ORCID,Meissburger Bettina5,Chan Jessica123,de Guia Roldan M.5,Mattijssen Frits123,Roessler Stephanie6,Birkenfeld Andreas L.378,Raschzok Nathanael9,Riols Fabien10,Tokarz Janina123,Giroud Maude123,Gil Lozano Manuel123,Hartleben Goetz123,Nawroth Peter12311,Haid Mark10,López Miguel412ORCID,Herzig Stephan12313ORCID,Berriel Diaz Mauricio123ORCID

Affiliation:

1. Institute for Diabetes and Cancer Helmholtz Center Munich 85764 Neuherberg Germany

2. Joint Heidelberg‐IDC Translational Diabetes Program Inner Medicine 1 University Hospital 69120 Heidelberg Germany

3. German Center for Diabetes Research (DZD) 85764 Neuherberg Germany

4. NeurObesity Group Department of Physiology CIMUS University of Santiago de Compostela‐Instituto de Investigación Sanitaria Santiago de Compostela 15782 Spain

5. Joint Division Molecular Metabolic Control DKFZ‐ZMBH Alliance and Network Aging Research German Cancer Research Center (DKFZ) 69120 Heidelberg Germany

6. Institute of Pathology Liver Cancer Center Heidelberg (LCCH) University Hospital Heidelberg Im Neuenheimer Feld 224 69120 Heidelberg Germany

7. Institute of Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich 72076 Tübingen Germany

8. Department of Diabetes School of Life Course Science King's College London London WC2R 2LS UK

9. Department of Surgery Campus Charité Mitte and Campus Virchow‐Klinikum Charité‐Universitätsmedizin Berlin 2, Berlin Institute of Health (BIH) 10117 Berlin Germany

10. Metabolomics and Proteomics Core Helmholtz Center Munich 85764 Neuherberg Germany

11. Department of Medicine 1 and Clinical Chemistry University of Heidelberg Im Neuenheimer Feld 410 69120 Heidelberg Germany

12. CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) Santiago de Compostela 15706 Spain

13. Chair Molecular Metabolic Control Technical University Munich Germany

Funder

Xunta de Galicia

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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