Pharmacological Inhibition of Core Regulatory Circuitry Liquid–liquid Phase Separation Suppresses Metastasis and Chemoresistance in Osteosarcoma-Reference-Cited by-同舟云学术

Pharmacological Inhibition of Core Regulatory Circuitry Liquid–liquid Phase Separation Suppresses Metastasis and Chemoresistance in Osteosarcoma

Published:2021-08-25 Issue:20 Volume:8 Page:2101895
ISSN:2198-3844
Container-title:Advanced Science
language:en
Short-container-title:Adv. Sci.

Author:

Lu Bing¹²,Zou Changye³,Yang Meiling¹,He Yangyang¹,He Jincan¹,Zhang Chuanxia²,Chen Siyun¹,Yu Jiaming¹,Liu Kilia Yun⁴,Cao Qi⁴⁵,Zhao Wei²^ORCID

Affiliation:

1. Key Laboratory of Stem Cells and Tissue Engineering (Sun Yat‐Sen University) Ministry of Education Guangzhou 510080 China

2. Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou 510080 China

3. Musculoskeletal Oncology Center The First Affiliated Hospital of Sun Yat‐Sen University Guangzhou 510080 China

4. Department of Urology Northwestern University Feinberg School of Medicine Chicago IL 60611 USA

5. Robert H. Lurie Comprehensive Cancer Center Northwestern University Feinberg School of Medicine Chicago IL 60611 USA

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Guangdong Innovative and Entrepreneurial Research Team Program

Natural Science Foundation of Guangdong Province

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.202101895

Reference24 articles.

1. SATB family chromatin organizers as master regulators of tumor progression

2. Super-Enhancers in the Control of Cell Identity and Disease

3. Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

4. Pol II phosphorylation regulates a switch between transcriptional and splicing condensates

5. Coactivator condensation at super-enhancers links phase separation and gene control

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