EGF Relays Signals to COP1 and Facilitates FOXO4 Degradation to Promote Tumorigenesis

Author:

Choi Hyun Ho12,Zou Shaomin12,Wu Jian‐lin3,Wang Huashe4,Phan Liem5,Li Kai12,Zhang Peng12,Chen Daici12,Liu Qingxin12,Qin Baifu12,Nguyen Thu Anh Thai6,Yeung Sai‐Ching J.7,Fang Lekun124,Lee Mong‐Hong12ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Disease The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou 510655 China

2. Guangdong Research Institute of Gastroenterology The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou 510655 China

3. State Key Laboratory of Quality Research in Chinese Medicine Macau Institute for Applied Research in Medicine and Health Macau University of Science and Technology Macao 999078 China

4. Department of Colorectal Surgery The Sixth Affiliated Hospital Sun Yat‐sen University Guangzhou 510655 China

5. Department of Molecular and Cellular Oncology Division of Basic Science Research The University of Texas MD Anderson Cancer Center Houston TX 77030 USA

6. Department of Biotechnology Nong Lam University Ho Chi Minh City 700000 Vietnam

7. Department of Emergency Medicine Division of Internal Medicine The University of Texas MD Anderson Cancer Center Houston TX 77030 USA

Funder

National Natural Science Foundation of China

Pearl River S and T Nova Program of Guangzhou

Natural Science Foundation of Guangdong Province

Fidelity Foundation

Publisher

Wiley

Subject

General Physics and Astronomy,General Engineering,Biochemistry, Genetics and Molecular Biology (miscellaneous),General Materials Science,General Chemical Engineering,Medicine (miscellaneous)

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